Nutrihuang.com TCM and Liver Cirrhosis for OEM
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Traditional Chinese Medicine for Liver Cirrhosis has Scientific Backing

The liver is a very important organ. It digests food (i.e. manufactures bile to help the body to digest food), synthesizing many important proteins, regulating blood clotting , store energy and detoxifies the body or break down potential toxic substances so that the body can use them. It can also do another amazing thing. It can regenerates itself. You cannot live without a functioning liver.

Hepatitis (liver cirrhosis) is a disease that attacks and affects the liver. There are many types of hepatitis that can cause liver cirrhosis. Liver cirrhosis  is a serious disease. The most common type of hepatitis are those caused by virus. There are five types of hepatitis: Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D and Hepatitis E. Hepatitis disease causes the liver to be inflamed. This inflammation can be acute, flaring up and then disappearing within a few weeks to months. For those who suffer from chronic hepatitis, the disease may simmer for more then 20 years without much symptoms except maybe a noticeable loss of energy and tiredness before causing significant symptoms related to progressive liver damage such as liver cirrhosis (scarring of the liver), liver failure, liver cancer, or death. In liver cirrhosis, scar tissue replaces normal, healthy tissue, blocking the flow of blood through the organ and preventing it from working as it should.

Causes

Viral Hepatitis: The initial source of this type of hepatitis comes from eating shellfish like clams and cockles contaminated with the virus. It is a disease common to fishermen and their families, coastal population and generally those who love to eat shellfish.

The disease spread through infected blood, contaminated needles, virginal secretions, seminal fluids, human bite, sexual contact, contaminated food and water, using articles contaminated by the virus like tooth brushes and from mother to child. Depending on the type of hepatitis virus, the incubation period ranges from 2 to 25 weeks.

Chemically-Induced Hepatitis: The liver is a very complex organ and is responsible for the metabolism of drugs, alcohol, and toxins from the environment. Some drugs or chemicals can cause liver damage whenever a person is exposed to them at high levels. Acetaminophen, which is found in many over-the-counter and prescription medications, is an example of this. In therapeutic doses, it is a useful pain reliever but unfortunately in very high dosages or if combined with alcohol, the drug can cause life-threatening acute liver failure. One of the most common causes of hepatitis is excessive consumption of alcohol, which by itself toxic to the liver. Other synthetic chemical that have had this affect include anesthetics, antibiotics, anabolic steroids, and seizure medications.

Iron Induced Hepatitis: Hemochromatosis hepatitis is caused by too much iron in the body. The liver is one of the principal organs damaged and chronic hepatitis may be due to hemochromatosis.

Inherited Hepatitis: Deficiency of alpha-1-antitrypsin is also a relatively common inherited disease.

Bile-induced Hepatitis: When the ducts that carry bile out of the liver are blocked, bile backs up and damages liver tissue. In babies, blocked bile ducts are most commonly caused by biliary atresia (where the bile ducts are absent or injured). In adults, primary biliary cirrhosis, is caused by inflamed, blocked, and scarred bile duct. Secondary biliary cirrhosis can happen after gallbladder surgery if the ducts are inadvertently tied off or injured.

Symptoms

The normal symptoms are:

  • Pain in the stomach,

  • Diarrhea,

  • Light stool,

  • Headache,

  • Muscle aches,

  • Loss of appetite,

  • Nausea,

  • Fever,

  • Fatigue,

  • Dark urine,

  • Abdominal pain,

  • Vomiting,

  • Jaundice (yellow skin and eyes)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Treatment

For prevention purposes vaccine maybe given to prevent some types of hepatitis virus but once a person contracted the diseases, synthetic chemicals cannot really help to treat the problems. In fact they may cause even more problems then resolving them. Our body does not really tolerate or handle synthetic chemical that well.

Herbal scientists are far more knowledgeable in treating this disease because of their vast historical clinical experience. Theirs are proven clinical scientific herbal technology based on actual clinical observation. These formulations are historically proven therapeutic effective products that has perfect after many generations of studies and they have been used by generations after generations of herbal scientists, benefiting thousands of fishermen and many who have been affected by the so called incurable disease as described by allopathic scientists.

Scientific research has showed and proven beyond a shadow of doubt the validity of these beliefs that herbs like Radix Rehmannia Glutinosa, Fructus Zanthii, Radix Glycyrrhiza Glabra, Flos Lonicera Japonica, Radix Scutellaria Baicalensis and Herba Artemisiae Scoparia have successfully been used to treat chronic hepatitis problems:

  • Chronic hepatitis

  • Cleanse and protect the liver

  • Hepatomegaly (enlarged liver and spleen)

  • Increase red blood cell production

  • Nourishes the blood

  • Protects the liver

  • Treats toxic effects caused by virus and bacteria

  • Improves function of the spleen

Radix Rehmannia Glutinosa: Clinical research by western scientists have shown that Chinese Rehmanniae Radix can prevent an inducement of impediment in the peripheral microcirculation of various chronic diseases through the improvement of hemorheology (blood flow). 12826

Glycyrrhiza Glabra:

This was part of the report sent by Dr. Minh-Tri Nguyen to Dr. Guełnaešl Rodier, Director, Department of Communicable Disease Surveillance and Response (CSR), WHO Headquarter  "Viruses are chemical particles having the ability to replicate only inside a living cell. Each virus particle or viron consist of a core of a single nucleic acid DNA or RNA surrounding by a protein coat and some cases by carbohydrates or lipids. Since viruses have no cellular organization, they have not cellular organism, have no nucleus, no cytoplasm and no surrounding  membrane, they are not alive but rather obligate parasites at genetic level (require a host cell in order to replicate). That is why antibiotics (anti=against, bio life) cannot kill coronaryviruses and consequently there is no possible vaccine for colds, influenza or SARS. Coronaryvirus (virus from Latin = poison) can be only counter-acted or neutralized by specific antidote herbs, which are highly suitable for human body." In the report to WHO he sighted that Radix Glycyrrhizae can be used for detoxification: neutralizes the poison produce by viruses and bacteria by action of  Glycyrrhizic acid C42 H62 O16

Licorice root extract has been used in Japan for more than twenty years as a treatment for chronic hepatitis. Results from randomized clinical trials using licorice root have shown a significant reduction of serum amino-transferase and a significant improvement in liver histology.11,12

11 Van Rossum TG, Vulto AG, de Man RA, Brouwer JT, Schalm SW. Review Article: glycyrrhizin as a potential treatment for chronic hepatitis C. Aliment Pharmacol Ther 1998 Mar; 12(3): 199-205.
12 Yamamura Y, Kotaki H, Tanaka N, Aikawa T, Sawada Y, Iga T. The pharmacokinetics of glycyrrhizin and its restorative effect on hepatic function in patients with chronic hepatitis and chronically carbon-tetrachloride intoxicated rats. Biopharm Drug Dispos 1997 Nov;18(8):717-25.

1) Clinical research by western scientists have shown that glycyrrhizin has inhibitory effects on immune-mediated cytotoxicity against hepatocytes and on nuclear factor (NF)-kappa B, which activates genes encoding inflammatory cytokines in the liver and can be used to treat hepatitis. 87634

2) Clinical research by western scientists have shown that this herb has strong anticarcinogenic capability. Aflatoxin B(1) (AFB(1)) causes oxidative stress and ROS formation via metabolic activation of AFB(1). Glycyrrhizic acid (GA) has been reported to have antioxidative properties. 67692

3) Clinical research by western scientists have shown that the decrease of elevated transaminase levels by glycyrrhizin in patients with chronic viral hepatitis is mediated in part by inhibition of immune-mediated cytotoxicity against hepatocytes. 42643

4) Clinical research by western scientists have shown that glycyrrhizin suppressed the intracellular transport of HBsAg at the trans-Golgi area after O-linked glycosylation and before its sialylation. Glycyrrhizin, a major component of a herb (licorice), has been widely used to treat chronic hepatitis B in Japan. 14808

5) Clinical research by western scientists have shown that Glycyrrhizin, an aqueous extract of licorice root, has anti-inflammatory activity and can be used for the treatment of chronic viral hepatitis.  Research showed that glycyrrhizin may prevent tissue injury caused by MAC not only in chronic hepatitis but in many autoimmune and inflammatory diseases. 92245

6) Clinical research by western scientists in a double blind placebo test have shown that active compounds in licorice root can be used to help prevent and treat chronic hepatitis (liver inflammation). 941500

7) Clinical research by western scientists have shown that (R)-4-(3,4-Dihydro-8,8-dimethyl)-2H,8H-benzo[1,2-b:3,4-b']dipyran-3yl)-1,3-benzenediol (glabridin), a flavonoid present in licorice extract, is known to have antimicrobial, anti-inflammatory, and cardiovascular protective activities. 312:1187

8) Clinical research by western scientists have shown that isoflavans from G. glabra were shown to be effective in protecting liver mitochondrial function against oxidative stresses. 14953

Scutellaria baicalensis:

1) Clinical research by western scientists have shown that saikosaponin-a, -d, baicalin from  Scutellaria baicalensis are potent antitumor components. 28;86(1):91-5

2) Clinical research by western scientists have shown that the flavones of Scutellaria baicalensis showed remarkable inhibitory effects on skin tumor. 40(2):531-3.

3) Clinical research by western scientists have shown that Scutellaria baicalensis' components, baicalein, baicalin, and wogonin, may become an attractive and promising treatment for bladder cancer because of its strong antioxidant effect.  55(6):951-5

4) Clinical research by western scientists have shown that Scutellaria baicalensis has anti-inflammatory and anti-cancer properties. Research showed that Scutellaria baicalensis selectively and effectively inhibits cancer cell growth in vitro and in vivo and can be an effective chemotherapeutic agent for HNSCC. Inhibition of PGE2 synthesis via suppression of COX-2 expression may be responsible for its anticancer activity.  4037-40

5) Western scientists has proven that Scutellaria baicalensis Georgi can be used to induce liver regeneration. Research showed that SbG stimulates hepatocyte growth via activation of the NF-B pathway and induces TGF-ß1 gene expression through the Kupffer cell–hepatocyte interaction, which subsequently results in the inhibition of SbG-stimulated hepatocyte growth. 231:444

6) Clinical research by western scientists have shown that this herb has strong anti-oxidant (anti-cancer) properties. Research showed that most of the anticancer activities of S. baicalensis can be recapitulated with four purified constituents that function in part through inhibition of the androgen receptor signaling pathway. 390539

7) Clinical research by western scientists has shown that Scutellaria baicalensis have anti-inflammatory functions, high scavenging activity and protects liver and red blood cells from lipid peroxidation. Research showed that extract of Scutellaria baicalensis showed inhibitory actions on aminopyrine N-demethylase and xanthine oxidase activities as well as an pro-oxidant effect observed in the Fe3+-EDTA-H2O2 system. 60151

Herba Artemisiae Scorparia:

1) Clinical research by western scientists have shown that this herb is effective for treating liver diseases.