1. Herba Lysimachia Christinae

Applications:

• It is used as febrifuge, cholagogue, lithagogue and diuretic for the treatment of acute icteric hepatitis, calculi of the biliary and urinary tracts.

Function of the herb:

• Counteract toxic effects to clear up liver heat expel urinary stones and promote urination

2. Radix Scutellaria Baicalensis

Applications:

• It is an important Chinese medicinal herb prescribed for fevers, colds, hypertension, insomnia, headaches, hepatitis, diphtheria, shingles, and other ailments.

Function of the herb:

• It is used to protect the liver
• It is used to induce liver regeneration
• It is used for the treatment of pyogenic infection. It is used for febrile diseases

1) Clinical studies by western scientists have shown that Scutellaria baicalensis has anti-inflammatory and anti-cancer properties. Research showed it selectively and effectively inhibits cancer cell growth in vitro and in vivo and can be an effective chemotherapeutic agent for HNSCC.  4037-4043,

2) Clinical studies by western scientists have proven that Scutellaria baicalensis can be used to induce liver regeneration. Research showed that Scutellaria baicalensis stimulated the proliferation of cultured hepatocytes. 444-455

3) Clinical studies by western scientists have shown that Scutellaria baicalensis has strong anti-oxidant (anti-cancer) properties. Research showed that most of the anticancer activities of Scutellaria baicalensis can be recapitulated with four purified constituents that function in part through inhibition of the androgen receptor signaling pathway.  3905-3914

4) Clinical research by western scientists have shown that Scutellaria baicalensis have anti-inflammatory functions, high scavenging activity and protects liver and red blood cells from lipid peroxidation. 60151

5) Clinical studies by western scientists have shown that saikosaponin-a, -d, baicalin from  Scutellaria baicalensis are potent antitumor components. 86(1):91-5

6) Clinical research by western scientists have shown that the flavones,  5,7,2'-trihydroxy- and 5,7,2',3'-tetrahydroxyflavone, of Scutellaria baicalensis showed remarkable inhibitory effects on skin tumor. 40(2):531-3.

7) Clinical research by western scientists have shown that Scutellaria baicalensis' components, baicalein, baicalin, and wogonin, may become an attractive and promising treatment for bladder cancer because of its strong antioxidant effect. 55(6):951-5

3. Radix Bupleurum Scorzonerifolium (Who's Firewood).

Applications:

Used as a prescribed medicine in combination with other herbs to treat cold, fever, malaria, gastrointestinal disorders and chronic liver diseases. Used for treatment of Cancer, Cirrhosis, Common cold, , Hepatitis, Infections, Inflammation, Liver disease and Malaria. Used to regulate the exterior and interior of the Liver, soothe the liver and cure drooping and ptosis. It has calming, pain relieving, antipyretic, heat reducing and anti inflammation, effects on the immune system, digestive system, heart and blood vessels and on excretion of urine. It also has anti tumor, anti bacteria, virus, and anti-amoeba effects on the metabolism.

Function of the herb:

• Disperse liver energy
• Protect liver
• Promote liver bile production
• Treat fatty liver
• Soften and shrink liver and spleen
• It is rich in saponins that reduce inflammation, regulate hormone level and is used for liver problems.

1) Clinical studies by western scientists have shown that Bupleurum scrozonerifolium has strong anti-oxidant (anti-cancer) properties. The result of in vivo study showed that Bupleurum scrozonerifolium could suppress growth in A549 subcutaneous xenograft tumors. 183-93

2) Clinical studies by western scientists have shown that Bupleurum scrozonerifolium has strong anti-oxidant (anti-cancer) properties. Research showed that the crude acetone extract of Bupleurum scorzonerifolium has anti-proliferation activity and apoptosis effects on human lung cancer cells.  2409-20

3) Clinical studies by western scientists have shown that saikosaponins, the main active constituents of Bupleurum spp., possess immunomodulatory, hepatoprotective, anti-tumor and anti-viral activities. Research showed that saikosaponin d possesses potent cytotoxicity against human hepatocellular carcinoma cells.  705-9

4) Clinical studies by western scientists have shown that Bupleurum scrozonerifolium improves cell function. 111-8

5) Clinical studies by western scientists have shown that two lignans, isochaihulactone and chaihunaphthone, from Bupleurum scrozonerifolium has  immunosuppressive functions. 1375-9

6) Clinical studies by western scientists have shown that Bupleurum scrozonerifolium protects and improves liver function. It has anti-inflammatory, anti-fibrotic, anti-oxidant activity and enhanced the liver cell regeneration. 442-8

7) Clinical studies by western scientists have shown that Bupleurum scrozonerifolium has strong antioxidative and in vitro hepatoprotective activity. It has anti-inflammatory, anti-oxidant activity and enhanced the liver cell regeneration. Research showed that the roots of  Bupleurum scrozonerifolium can be used to treat liver diseases. 1003-8

4. Folium Artemisa Scoparia

Applications:

• It is used to eliminate damp heat in the liver and gall bladder for the treatment of jaundice such as icteric hepatitis and cholecystitis

Function of the herb:

• It is used to eliminate damp heat in the liver and jaundice caused by hepatitis
• It is used to protect the liver
• It is used to promote liver bile production and excretion
• It is used as an antiviral herb
• It is used as an adjuvant herb to treat liver and gall bladder disease

1) Clinical research by western scientists have shown that Artemisiae species were proven to have immunosuppressive principles and can be used clinically for the treatment of rheumatoid arthritis. 41992

2) Clinical studies by western scientists have shown that Artemisa Scoparia is effective for treating hepatitis (liver cirrhosis). Research showed that scoparone from Artemisa Scoparia decreases the production of the inflammatory mediators such as NO and PGE2 in macrophages by inhibiting iNOS and COX-2 expression. 203-8 

3) Another group of scientists wrote "these data indicate that the plant Artemisia Scoparia is hepatoprotective and validate the folkloric use of this plant in liver damage". Research showed the protective action of the plant extract against CCl4-induced liver damage.  41001

4) Clinical studies by western scientists have shown that Artemisia Scoparia has strong anti-inflammatory function. Research demonstrate that the inhibition of scoparone on LPS-induced TF expression in HUVECs may mediate by the mechanisms suppressing superoxide anion formation and TF transcription. 72379

5) Clinical studies by western scientists have shown that Artemisia Scoparia  has strong hepatoprotective function against alcohol-induced hepatotoxicity. 75379

6) Clinical studies by western scientists have shown that the flavonoid rutin from Artemisia Scoparia  has strong hepatoprotective function against drug-induced (paracetamol) hepatotoxicity. 90212

7) Clinical studies by western scientists have shown that Artemisia Scoparia  has strong hepatoprotective function against drug-induced (Acetaminophen) hepatotoxicity.  12519

8) Clinical studies by western scientists have shown that Artemisia Scoparia  has strong hepatoprotective function against chemical-induced (carbon tetrachloride) hepatotoxicity. Research showed that Artemisia Scoparia inhibited fibrosis and lipid peroxidation induced by carbon tetrachloride.  33139

9) Clinical studies by western scientists have shown that Artemisia Scoparia  has strong antioxidative and cytoprotective actions. Clinical studies showed that the strong antioxidative functions of Artemisia Scoparia effectively protected liver tissues against the dimethylnitrosamine-induced hepatic fibrosis.  06248

5. Radix Glycyrrhiza Glabra

Applications:

• Invigorates the function of the spleen
• It is used as an antitoxin

Function of the herb:

• Cleanse and protect the liver
• Promotes production of red blood cells
• Invigorates the function of the heart and the spleen
• Improves the vital energy
• Improves the immune system
• Improves cell functions of liver
• Promote immunology

1) Clinical research by western scientists from Hong Kong have shown that Glycyrrhiza glabra has strong anticarcinogenic capability. Glycyrrhiza glabra was able to inhibit the metabolic activation of hepato-toxin, a critical factor in the pathogenesis of chemical-induced carcinogenicity. 12767692

2) Clinical research by western scientists have shown that Glycyrrhiza glabra has strong cell protective function from oxidative stresses. Research showed that dihydroxyfumarate-induced mitochondrial peroxidation was prevented by isoflavans from Glycyrrhiza glabra.  14953

3) Clinical research by western scientists have shown that glycyrrhizin from Glycyrrhiza glabra may prevent tissue injury caused by MAC not only in chronic hepatitis but in many autoimmune and inflammatory diseases. 92245

4) Previous clinical research by western scientists have shown that (R)-4-(3,4-Dihydro-8,8-dimethyl)-2H,8H-benzo[1,2-b:3,4-b']dipyran-3yl)-1,3-benzenediol (glabridin), a flavonoid present in licorice extract, have antimicrobial, anti-inflammatory, and cardiovascular protective activities. This research showed that glabridin inhibits NO production and iNOS gene expression by blocking NF-B/Rel activation and that glabridin was shown to have anti-inflammatory functions.   1187-1194

5) Double blind clinical research by western scientists over a period of 10 years have shown that active compounds in licorice root can be used to help prevent and treat chronic viral hepatitis C (liver inflammation). 1494–1500

6) Clinical research by western scientists have shown that glycyrrhizin, a major component of a herb (licorice), has been widely used to treat chronic hepatitis B in Japan. 14808

7) Clinical research by western scientists have shown that glycyrrhizin has inhibitory effects on immune-mediated cytotoxicity against hepatocytes and on nuclear factor (NF)-kappa B, which activates genes encoding inflammatory cytokines in the liver and can be used to treat hepatitis. 87634

8) Clinical research by western scientists have shown that the decrease of elevated transaminase levels by glycyrrhizin is mediated in part by inhibition of immune-mediated cytotoxicity against hepatocytes (glycyrrhizin improves liver functions).  42643

9) Clinical studies by western scientists have shown that glycyrrhizic acid from licorice is able to inhibit cytotocity produced by aflatoxin B1 (it is a fungal toxin which is a powerful liver carcinogen). 7692

10) Clinical research by western scientists have shown that the flavonoid of licorice, flavones, flavonals, isoflavones, chalcones, bihydroflavones and bihydrochalcones, have antioxidant, antibacterial, antitumer and inhibiting HIV activities.  593-7

11) Clinical research by western scientists have shown that Glycyrrhiza glabra protects liver mitochondria against oxidative stresses. Mitochondrial lipid peroxidation linked to respiratory electron transport and that induced non-enzymatically were inhibited by the herb. 219-23.